Nitric Oxide Donation Lowers Blood Pressure in Adrenocorticotrophic Hormone-Induced Hypertensive Rats
Date
2004
Authors
Andrews, Miles
Schyvens, Chris
Zhang, Yi
McKenzie, Katja
Whitworth, Judith
Journal Title
Journal ISSN
Volume Title
Publisher
Informa Healthcare
Abstract
Adrenocorticotrophic hormone (ACTH) elevates systolic blood pressure (SBP) and lowers plasma reactive nitrogen intermediates in rats. We assessed the ability of NO donation from isosorbide dinitrate (ISDN) to prevent or reverse the hypertension caused by
Description
Keywords
Keywords: corticotropin; drinking water; glucocorticoid; isosorbide dinitrate; nitrate; nitric oxide; adrenal cortex; animal model; article; blood pressure; blood pressure measurement; controlled study; drug effect; hormonal regulation; hypertension; male; nonhuman Adrenocorticotrophic hormone; Glucocorticoids; Hypertension; Isosorbide dinitrate; Nitric oxide
Citation
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Source
Clinical and Experimental Hypertension
Type
Journal article