Radical Carboxyarylation Approach to Lignans. Total Synthesis of (-)-Arctigenin, (-)-Matairesinol, and Related Natural Products

Date

2004

Authors

Fischer, Joshua
Reynolds, Aaron
Sharp, Lisa
Sherburn, Michael

Journal Title

Journal ISSN

Volume Title

Publisher

American Chemical Society

Abstract

Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (-)-matairesinol, and (-)α-conidendrin, by way of a highly stereoselective domino radical sequence is presented. The reported stereochemistry of the natura

Description

Keywords

Keywords: 7 hydroxyarctigenin; arctigenin; conidendrin; lignan derivative; matairesinol; plant extract; unclassified drug; article; arylation; controlled study; diastereoisomer; drug structure; drug synthesis; nonhuman; stereochemistry; Antineoplastic Agents; Antiv

Citation

Source

Organic Letters

Type

Journal article

Book Title

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