Radical Carboxyarylation Approach to Lignans. Total Synthesis of (-)-Arctigenin, (-)-Matairesinol, and Related Natural Products
Date
2004
Authors
Fischer, Joshua
Reynolds, Aaron
Sharp, Lisa
Sherburn, Michael
Journal Title
Journal ISSN
Volume Title
Publisher
American Chemical Society
Abstract
Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (-)-matairesinol, and (-)α-conidendrin, by way of a highly stereoselective domino radical sequence is presented. The reported stereochemistry of the natura
Description
Keywords
Keywords: 7 hydroxyarctigenin; arctigenin; conidendrin; lignan derivative; matairesinol; plant extract; unclassified drug; article; arylation; controlled study; diastereoisomer; drug structure; drug synthesis; nonhuman; stereochemistry; Antineoplastic Agents; Antiv
Citation
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Source
Organic Letters
Type
Journal article