Presynaptic Ca2+ channels: a functional patchwork
A key step in the release of neurotransmitter is the entry of Ca 2+ into the presynaptic terminal via voltage-activated Ca 2+ channels. N-type and P/Q-type Ca2+ channels play a predominant role but, surprisingly, their distribution across presynaptic terminals lacks any apparent order. They form a patchwork: at some terminals only N-type channels contribute to transmitter release and in others only P/Q-type channels contribute, but in many terminals both sub-types are active. The physiological...[Show more]
|Collections||ANU Research Publications|
|Source:||Trends in Neurosciences|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.