Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9- O -sulfate from an Indonesian Aaptos sp. marine sponge
Date
2004
Authors
Herlt, Anthony
Mander, Lewis
Rombang, Wilson
Rumampuk, Rymond
Soemitro, Soetijoso
Steglich, Wolfgang
Tarigan, Ponis
von Nussbaum, Franz
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.
Description
Keywords
Keywords: aaptamine; bisnoraaptamine 9 o sulfate; unclassified drug; analytic method; article; comparative study; high performance liquid chromatography; Indonesia; isolation procedure; nonhuman; priority journal; spectroscopy; sponge (Porifera); synthesis; Aaptos Aaptos; Bisdemethylaaptamine; Sulfated aaptamines
Citation
Collections
Source
Tetrahedron
Type
Journal article