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Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease

Larter, Claire; Yeh, Matthew; Haigh, W Geoffrey; Van Rooyen, Derrick; Brooling, John; Heydet, Deborah; Nolan, Christopher; Teoh, Narcissus; Farrell, Geoffrey

Description

Background: Alms1 mutant (foz/foz) mice develop hyperphagic obesity, diabetes, metabolic syndrome, and fatty liver (steatosis). High-fat (HF) feeding converts pathology from bland steatosis to nonalcoholic steatohepatitis (NASH) with fibrosis, which leads

dc.contributor.authorLarter, Claire
dc.contributor.authorYeh, Matthew
dc.contributor.authorHaigh, W Geoffrey
dc.contributor.authorVan Rooyen, Derrick
dc.contributor.authorBrooling, John
dc.contributor.authorHeydet, Deborah
dc.contributor.authorNolan, Christopher
dc.contributor.authorTeoh, Narcissus
dc.contributor.authorFarrell, Geoffrey
dc.date.accessioned2015-12-13T22:39:14Z
dc.identifier.issn1930-7381
dc.identifier.urihttp://hdl.handle.net/1885/77691
dc.description.abstractBackground: Alms1 mutant (foz/foz) mice develop hyperphagic obesity, diabetes, metabolic syndrome, and fatty liver (steatosis). High-fat (HF) feeding converts pathology from bland steatosis to nonalcoholic steatohepatitis (NASH) with fibrosis, which leads
dc.publisherNature Publishing Group
dc.sourceObesity
dc.subjectKeywords: adenosine triphosphate; alanine aminotransferase; CD36 antigen; cholesterol ester; fatty acid; immunoglobulin enhancer binding protein; triacylglycerol; uncoupling protein 2; adipose tissue; alanine aminotransferase blood level; animal cell; animal experi
dc.titleDietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume21
dc.date.issued2013
local.identifier.absfor110307 - Gastroenterology and Hepatology
local.identifier.absfor110316 - Pathology
local.identifier.absfor110306 - Endocrinology
local.identifier.ariespublicationf5625xPUB6505
local.type.statusPublished Version
local.contributor.affiliationLarter, Claire, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationYeh, Matthew, University of Washington
local.contributor.affiliationHaigh, W Geoffrey, University of Washington
local.contributor.affiliationVan Rooyen, Derrick, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBrooling, John, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationHeydet, Deborah, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationNolan, Christopher, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationTeoh, Narcissus, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationFarrell, Geoffrey, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue6
local.bibliographicCitation.startpage1189
local.bibliographicCitation.lastpage1199
local.identifier.doi10.1002/oby.20123
dc.date.updated2016-02-24T09:29:49Z
local.identifier.scopusID2-s2.0-84881375574
local.identifier.thomsonID000322487000019
CollectionsANU Research Publications

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