Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease
Date
2013
Authors
Larter, Claire
Yeh, Matthew
Haigh, W Geoffrey
Van Rooyen, Derrick
Brooling, John
Heydet, Deborah
Nolan, Christopher
Teoh, Narcissus
Farrell, Geoffrey
Journal Title
Journal ISSN
Volume Title
Publisher
Nature Publishing Group
Abstract
Background: Alms1 mutant (foz/foz) mice develop hyperphagic obesity, diabetes, metabolic syndrome, and fatty liver (steatosis). High-fat (HF) feeding converts pathology from bland steatosis to nonalcoholic steatohepatitis (NASH) with fibrosis, which leads
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Keywords
Keywords: adenosine triphosphate; alanine aminotransferase; CD36 antigen; cholesterol ester; fatty acid; immunoglobulin enhancer binding protein; triacylglycerol; uncoupling protein 2; adipose tissue; alanine aminotransferase blood level; animal cell; animal experi
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Source
Obesity
Type
Journal article
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Restricted until
2037-12-31
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