Polymorphisms in IL-4Ralpha Correlate with Airways Hyperreactivity, Eosinophilia, and Ym Protein Expression in Allergic IL-13-/- Mice
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Webb, Dianne
Matthaei, Klaus
Cai, Yeping
Mckenzie, Andrew N
Foster, Paul S
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American Association of Immunologists
Abstract
The development of airways hyperreactivity in allergic IL-13-/- mice is controversial and appears to correlate with the number of times that the original 129 × C57BL/6 founder strain has been crossed to the BALB/c background. In this investigation, we co
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Journal of Immunology