Studies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis
Date
2013
Authors
Tjhin, Erick
Staines, Henry M.
Van Schalkwyk, Donelly
Krishna, Sanjeev
Saliba, Kevin
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Elsevier
Abstract
To characterise plasmodial glycolysis, we generated two transgenic Plasmodium falciparum lines, one expressing P. falciparum hexokinase (PfHK) tagged with GFP (3D7-PfHKGFP) and another overexpressing native PfHK (3D7-PfHK+). Contrary to previous reports,
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Keywords
Keywords: deoxyglucose; glucose; glucose transporter; hexokinase; article; cellular distribution; controlled study; cytosol; enzyme activity; glucose transport; glycolysis; nonhuman; Plasmodium falciparum; priority journal; transgenic organism; Glucose; Hexokinase; Glucose; Hexokinase; Hexose transport; Malaria; Plasmodium
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Source
FEBS Letters
Type
Journal article
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2037-12-31
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