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Glutathione transferase Omega 1 is required for the lipopolysaccharide- stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages

Menon, Deepthi; Coll, Rebecca; O'Neill, Luke A J; Board, Philip

Description

Bacterial lipopolysaccharide (LPS) stimulation of macrophages and inflammation via the Toll-like receptor 4 (TLR4) signaling pathway through NF-κΒ generates reactive oxygen species (ROS) and proinflammatory cytokines such as IL-1β, IL-6, and TNFα. Bec

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/73867
Source: Free Radical Biology and Medicine
DOI: 10.1016/j.freeradbiomed.2014.05.020

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