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Glutathione transferase Omega 1 is required for the lipopolysaccharide- stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages

Menon, Deepthi; Coll, Rebecca; O'Neill, Luke A J; Board, Philip

Description

Bacterial lipopolysaccharide (LPS) stimulation of macrophages and inflammation via the Toll-like receptor 4 (TLR4) signaling pathway through NF-κΒ generates reactive oxygen species (ROS) and proinflammatory cytokines such as IL-1β, IL-6, and TNFα. Bec

dc.contributor.authorMenon, Deepthi
dc.contributor.authorColl, Rebecca
dc.contributor.authorO'Neill, Luke A J
dc.contributor.authorBoard, Philip
dc.date.accessioned2015-12-13T22:27:15Z
dc.identifier.issn0891-5849
dc.identifier.urihttp://hdl.handle.net/1885/73867
dc.description.abstractBacterial lipopolysaccharide (LPS) stimulation of macrophages and inflammation via the Toll-like receptor 4 (TLR4) signaling pathway through NF-κΒ generates reactive oxygen species (ROS) and proinflammatory cytokines such as IL-1β, IL-6, and TNFα. Bec
dc.publisherElsevier BV
dc.sourceFree Radical Biology and Medicine
dc.titleGlutathione transferase Omega 1 is required for the lipopolysaccharide- stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume73
dc.date.issued2014
local.identifier.absfor060100 - BIOCHEMISTRY AND CELL BIOLOGY
local.identifier.absfor060199 - Biochemistry and Cell Biology not elsewhere classified
local.identifier.absfor110300 - CLINICAL SCIENCES
local.identifier.ariespublicationU3488905xPUB3865
local.type.statusPublished Version
local.contributor.affiliationMenon, Deepthi, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationColl, Rebecca, Trinity College Dublin 2
local.contributor.affiliationO'Neill, Luke A J, Trinity College Dublin 2
local.contributor.affiliationBoard, Philip, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage318
local.bibliographicCitation.lastpage327
local.identifier.doi10.1016/j.freeradbiomed.2014.05.020
dc.date.updated2015-12-11T08:29:56Z
local.identifier.scopusID2-s2.0-84903278627
local.identifier.thomsonID000339695600032
CollectionsANU Research Publications

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