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Characterization of the Omega Class of Glutathione Transferases

Whitbread, Astrid; Masoumi, Amir; Tetlow, Natasha; Schmuck, Erica; Coggan, Marjorie; Board, Philip


The Omega class of cytosolic glutathione transferases was initially recognized by bioinformatic analysis of human sequence databases, and orthologous sequences were subsequently discovered in mouse, rat, pig, Caenorhabditis elegans, Schistosoma mansoni, and Drosophila melanogaster. In humans and mice, two GSTO genes have been recognized and their genetic structures and expression patterns identified. In both species, GSTO1 mRNA is expressed in liver and heart as well as a range of other...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Book chapter
Book Title: Glutathione Transferases and Gamma-Glutamyl Transpeptidases
DOI: 10.1016/S0076-6879(05)01005-0


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