Consecutive gold(I)-catalyzed cyclization reactions of o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas: A one-pot synthesis of pyrimido[1,6- a ]indol-1(2 H)-ones and related systems

Date

2013

Authors

Sharp, Phillip
Banwell, Martin
Renner, Jens
Lohmann, Klaas
Willis, Anthony

Journal Title

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Volume Title

Publisher

American Chemical Society

Abstract

Treatment of readily available o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas such as 1 with the Au(I)-catalyst 11 affords, via a twofold cyclization process, the isomeric pyrimido[1,6-a]indol-1(2H)-one 3 in good yield.

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Source

Organic Letters

Type

Journal article

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Restricted until

2037-12-31