CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse
Date
2013
Authors
Wiede, Florian
Fromm, Phillip
Comerford, Iain
Kara, Ervin
Bannan, Jennifer
Schuh, Wolfgang
Tarlinton, David M.
Winkler, Thomas
McColl, Shaun
Korner, Heinrich
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Volume Title
Publisher
Blackwell Publishing Ltd
Abstract
The CC-chemokine receptor 6 (CCR6) is expressed constitutively at an intermediate level on naïve B cells and is upregulated after activation on pregerminal center (GC) B cells. We hypothesized that it could be involved in the events leading to GC reactio
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Keywords
Keywords: chemokine receptor CCR6; keyhole limpet hemocyanin; animal cell; animal experiment; antibody production; article; B lymphocyte activation; B lymphocyte differentiation; cell maturation; controlled study; germinal center; immunohistology; in vivo study; mo B cells; chemokine receptor; germinal centers
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Source
Immunology and Cell Biology
Type
Journal article
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Restricted until
2037-12-31
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