Role of T-type channels in vasomotor function: Team player or chameleon?
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Kuo, Ivana; Howitt, Lauren; Sandow, Shaun, L; McFarlane, Alexandra; Hansen, Pernille; Hill, Caryl
Description
Low-voltage-activated T-type calcium channels play an important role in regulating cellular excitability and are implicated in conditions, such as epilepsy and neuropathic pain. T-type channels, especially Cav3.1 and Cav3.2, are also expressed in the vasculature, although patch clamp studies of isolated vascular smooth muscle cells have in general failed to demonstrate these low-voltage-activated calcium currents. By contrast, the channels which are blocked by T-type channel antagonists are...[Show more]
Collections | ANU Research Publications |
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Date published: | 2014 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/71179 |
Source: | Pflugers Archives European Journal of Physiology |
DOI: | 10.1007/s00424-013-1430-x |
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02_Kuo_Role_of_T-type_channels_in_2014.pdf | 175.95 kB | Adobe PDF | Request a copy |
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