Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation
Poon, Ivan K.A.; Goodall, Katherine J.; Phipps, Simon; Chow, Jenny D Y; Pagler, Eloisa; Andrews, Daniel M; Conlan, Carly L; Ryan, Gemma F; White, Julie A; Wong, Michael K L; Horan, Catherine; Matthaei, Klaus; Smyth, Mark J; Hulett, Mark
Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both normal physiological and pathological processes, including
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|Source:||European Journal of Immunology|
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