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Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

Poon, Ivan K.A.; Goodall, Katherine J.; Phipps, Simon; Chow, Jenny D Y; Pagler, Eloisa; Andrews, Daniel M; Conlan, Carly L; Ryan, Gemma F; White, Julie A; Wong, Michael K L; Horan, Catherine; Matthaei, Klaus; Smyth, Mark J; Hulett, Mark

Description

Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both normal physiological and pathological processes, including

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/69967
Source: European Journal of Immunology
DOI: 10.1002/eji.201343645

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