Modulation of dendritic synaptic processing in the lateral superior olive by hyperpolarization-activated currents
We have previously shown that mice lateral superior olive (LSO) neurons exhibit a large hyperpolarization-activated current (Ih), and that hyperpolarization-activated cyclic-nucleotide-gated type 1 channels are present in both the soma and dendrites of these cells. Here we show that the dendritic Ih in LSO neurons modulates the integration of multiple synaptic inputs. We tested the LSO neuron's ability to integrate synaptic inputs by evoking excitatory post-synaptic potentials (EPSPs) in...[Show more]
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|Source:||European Journal of Neuroscience|
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