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The Role of Fas Ligand in Beta Cell Destruction in Autoimmune Diabetes of NOD Mice

Petrovsky, Nikolai; Silva, D; Socha, L; Slattery, Robyn; Charlton, Brett

Description

Fas ligand (FasL), a type 2 membrane protein belonging to the TNF family, plays an important role in the induction of cell death. Ligation of Fas receptors by FasL results in apoptosis of the Fas-expressing cell. Autoimmune diabetes results from β cell d

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/67743
Source: Annals of the New York Academy of Sciences

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