Skip navigation
Skip navigation

The Role of Fas Ligand in Beta Cell Destruction in Autoimmune Diabetes of NOD Mice

Petrovsky, Nikolai; Silva, D; Socha, L; Slattery, Robyn; Charlton, Brett

Description

Fas ligand (FasL), a type 2 membrane protein belonging to the TNF family, plays an important role in the induction of cell death. Ligation of Fas receptors by FasL results in apoptosis of the Fas-expressing cell. Autoimmune diabetes results from β cell d

dc.contributor.authorPetrovsky, Nikolai
dc.contributor.authorSilva, D
dc.contributor.authorSocha, L
dc.contributor.authorSlattery, Robyn
dc.contributor.authorCharlton, Brett
dc.date.accessioned2015-12-10T23:26:24Z
dc.identifier.issn0077-8923
dc.identifier.urihttp://hdl.handle.net/1885/67743
dc.description.abstractFas ligand (FasL), a type 2 membrane protein belonging to the TNF family, plays an important role in the induction of cell death. Ligation of Fas receptors by FasL results in apoptosis of the Fas-expressing cell. Autoimmune diabetes results from β cell d
dc.publisherNew York Academy of Sciences
dc.sourceAnnals of the New York Academy of Sciences
dc.subjectKeywords: cytokine; FAS ligand; animal experiment; animal model; apoptosis; autoimmune disease; cell destruction; conference paper; controlled study; cytokine release; flow cytometry; immunohistochemistry; insulin dependent diabetes mellitus; mouse; mouse strain; n Apoptosis; Autoimmunity; Diabetes; Fas; Fas ligand; NOD mice
dc.titleThe Role of Fas Ligand in Beta Cell Destruction in Autoimmune Diabetes of NOD Mice
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume958
dc.date.issued2002
local.identifier.absfor110703 - Autoimmunity
local.identifier.ariespublicationMigratedxPub1513
local.type.statusPublished Version
local.contributor.affiliationPetrovsky, Nikolai, Flinders Medical Centre
local.contributor.affiliationSilva, D, University of Sydney
local.contributor.affiliationSocha, L, University of Canberra
local.contributor.affiliationSlattery, Robyn, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCharlton, Brett, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage204
local.bibliographicCitation.lastpage208
dc.date.updated2015-12-10T10:59:44Z
local.identifier.scopusID2-s2.0-0036276370
CollectionsANU Research Publications

Download

File Description SizeFormat Image
01_Petrovsky_The_Role_of_Fas_Ligand_in_Beta_2002.pdf725.63 kBAdobe PDF    Request a copy
02_Petrovsky_The_Role_of_Fas_Ligand_in_Beta_2002.pdf725.63 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator