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Sunlight and vitamin D affect DNA damage, cell division and cell death in human lymphocytes: A cross-sectional study in South Australia

Nair-Shalliker, Visalini; Fenech, Michael; Forder, Peta M; Clements, Mark; Armstrong, Bruce K

Description

The ultraviolet (UV)-B spectrum in solar UV radiation is essential for stimulating the epidermal production of vitamin D but also damages DNA and causes cancer in exposed cells.We examined the role of solarUVin inducingDNAdamage inblood lymphocytes and the possible modulation of this damage by serum 25-hydroxy vitaminD(25(OH)D) in 207male and female participants from South Australia. Personal solar UVexposure was estimated from hours of outdoor exposure recalled at the time of blood collection...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/67290
Source: Mutagenesis
DOI: 10.1093/mutage/ges026

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