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Unravelling the mysteries of protein folding and misfolding

Ecroyd, Heath; Carver, John


This mini-review focuses on the processes and consequences of protein folding and misfolding. The latter process often leads to protein aggregation and precipitation with the aggregates adopting either highly ordered (amyloid fibril) or disordered (amorphous) forms. In particular, the amyloid fibril is discussed because this form has gained considerable notoriety due to its close links to a variety of debilitating diseases including Alzheimer's, Parkinson's, Huntington's, and Creutzfeldt-Jakob...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: IUBMB Life
DOI: 10.1002/iub.117


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