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DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo

Da'Dara, Akram A.; Li, Yue-Sheng; Xiong, Tie; Zhou, Jie; Williams, Gail; McManus, Donald P.; Feng, Zeng; Yu, Xin-Ling; Gray, Darren; Harn, Donald A.


Schistosomiasis japonica is an endemic, zoonotic disease of major public health importance in China where water buffaloes account for approximately 75% of disease transmission. Interventions that reduce schistosome infection in water buffaloes will enhance their health simultaneously reducing disease transmission to humans. While chemotherapy has proved successful, it requires continued time consuming and expensive mass treatments. A more sustainable option would be development of vaccines that...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Vaccine
DOI: 10.1016/j.vaccine.2008.04.080


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