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De novo infantile primary antiphospholipid antibody syndrome

Alshekaili, Jalila; Reynolds, Graham; Cook, Matthew


Most autoimmune diseases are rare in infants. Early onset can represent an extreme phenotype arising from strong genetic predisposition relatively independent of environmental influence. Alternatively, neonatal autoimmunity can arise from transplacental passage of maternal pathogenic IgG autoantibodies. Distinguishing between these possible explanations is crucial for determining the prognosis in the specific patient, and has important implications for understanding pathogenesis. We report a...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: LUPUS
DOI: 10.1177/0961203310375263


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