Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans

Vella, Peter; Miraula, Manfredi; Phelan, Emer; Leung, Eleanor W W; Ely, Fernanda; Ollis, David; McGeary, Ross Peter; Schenk, Gerhard; Mitic, Natasa

Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans

Date

2013

Authors

Vella, Peter

Miraula, Manfredi

Phelan, Emer

Leung, Eleanor W W

Ely, Fernanda

Ollis, David

McGeary, Ross Peter

Schenk, Gerhard

Mitic, Natasa

Publisher

Springer

Abstract

Metallo-β-lactamases (MBLs) are a family of metalloenzymes that are capable of hydrolyzing β-lactam antibiotics and are an important means by which bacterial pathogens use to inactivate antibiotics. A database search of the available amino acid sequence