Probing for the pharmacophore of the cytotoxic neoclerodane salvileucalin B
Date
2012
Authors
Heinrich, Nora
Banwell, Martin
Willis, Anthony
Cade, Ian
Capon, Robert J
Huang, Xiao-Cong
Journal Title
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Volume Title
Publisher
CSIRO Publishing
Abstract
The novel [4.3.1]propelladiene 2, which embodies the key structural elements of the pentacyclic core of the cytotoxic neoclerodane salvileucalin B (1), has been prepared using a rhodium-catalysed intramolecular Bchner reaction as the key step. Compound 2
Description
Keywords
Keywords: Cytotoxic; Human cancer cells; Pharmacophores; Structural elements; Cell culture; Rhodium
Citation
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Source
Australian Journal of Chemistry
Type
Journal article
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DOI
Restricted until
2037-12-31