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Effect of proton pump inhibitors on markers of risk for high-grade dysplasia and oesophageal cancer in Barrett's oesophagus

Hillman, Lybus; Chiragakis, Louise; Shadbolt, Bruce; Kaye, G L; Clarke, Anthony


Background: It has been shown that the presence on diagnosis of endoscopic macroscopic markers indicates a high-risk group for Barrett's oesophagus. Aim: To determine whether proton pump inhibitor therapy prior to diagnosis of Barrett's oesophagus influences markers for risk development of subsequent high-grade dysplasia/adenocarcinoma. Methods: A review of all patients with Barrett's oesophagus entering a surveillance programme was undertaken. Five hundred and two patients diagnosed with...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Alimentary pharmacology & therapeutics
DOI: 10.1111/j.1365-2036.2007.03579.x


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