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Final results of Australasian Gastrointestinal Trials Group ARCTIC study: an audit of raltitrexed for patients with cardiac toxicity induced by fluoropyrimidines

Ransom, D.; Wilson, K.; Fournier, M.; Simes, R John; Gebski, Val; Yip, Desmond; Tebbutt, N.; Karapetis, C.S.; Ferry, D.; Gordon, S.; Price, T.J.


Background: Cardiac toxicity an uncommon but serious side-effect of some fluoropyrimides. Cardiac toxicity from raltitrexed is rarely reported. With this background, we initiated this study to investigate the incidence of cardiac events in patients who had switched to raltitrexed following cardiac toxicity from fluoropyrimidines (5-fluorouracil or capecitabine). Patients and methods: Pharmacy records were used to identify patients receiving raltitrexed from January 2004 till March 2012. Medical...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Annals of Oncology
DOI: 10.1093/annonc/mdt479.


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