Regression of Novikoff rat hepatocellular carcinoma following locoregional administration of a novel formulation of clofazimine in lipiodol
Date
2004
Authors
Pourgholami, Mohammad H
Lu, Ying
Wang, Lisa
Stephens, Ross
Morris, David L
Journal Title
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Volume Title
Publisher
Elsevier
Abstract
We report here that, clofazimine (CFZ) treatment (0.1-10 μM) led to inhibition of in vitro proliferation of hepatocellular carcinoma (HCC) cell lines Hep3-β, HuH-7, HepG2, SKHEP-1, PLC/PRF-5 and Novikoff. A 24 h exposure of human HuH-7 cells to various
Description
Keywords
Keywords: clofazimine; iodinated poppyseed oil; animal cell; animal experiment; animal model; animal tissue; apoptosis; article; cancer inhibition; controlled study; drug efficacy; histopathology; human; human cell; intestine; lipophilicity; liver cell carcinoma; l Clofazimine; Hepatocellular carcinoma; Lipiodol; Novikoff
Citation
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Source
Cancer Letters
Type
Journal article
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2037-12-31