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MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

Humphreys, David T; Westman, Belinda J; Martin, David I K; Preiss, Thomas


MicroRNAs (miRNAs) repress translation of target mRNAs by interaction with partially mismatched sequences in their 3′ UTR. The mechanism by which they act on translation has remained largely obscure. We examined the translation of mRNAs containing four

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.0506482102


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