Construction and evaluation of live attenuated myxoma virus vaccines with targeted virulence gene deletions
Date
2008
Authors
Adams, Mathew
van Leeuwen, Barbara
Kerr, P J
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Publisher
Elsevier
Abstract
Three deletion mutant viruses were constructed as potential vaccines against myxomatosis using the naturally attenuated Uriarra strain of myxoma virus. The viruses had the M007 (encodes a secreted γ-interferon receptor homologue), M010 (encodes an epider
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Keywords
Keywords: epidermal growth factor; gamma interferon receptor; inhibitor of apoptosis protein; live vaccine; Myxoma virus Ur delta m007 vaccine; Myxoma virus Ur delta m10 m11 vaccine; Myxoma virus Ur triple gene knockout vaccine; unclassified drug; animal cell; anim Myxoma virus; Myxomatosis; Poxvirus; Vaccine
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Source
Vaccine
Type
Journal article
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Restricted until
2037-12-31
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