Potas, Jason; Zheng, Yu; Moussa, Charbel; Venn, Melinda; Gorrie, Catherine A; Deng, Chao; Waite, P M E
The immune response contributes to ongoing secondary tissue destruction following spinal cord injury (SCI). Although infiltrating neutrophils and monocytes have been well studied in this process, T-cells have received less attention. The objective of this study was to assess locomotor recovery and tissue morphology after SCI in athymic (nude) rats, in which T-cell numbers are reduced. Results in athymic rats were compared with heterozygote littermates with normal T-cell profiles and with...[Show more]
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