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Cytotoxic T cells are the predominant players providing cross-protective immunity induced by {gamma}-irradiated influenza A viruses

Furuya, Yoichi; Chan, Jennifer; Regner, Matthias; Lobigs, Mario; Koskinen, Aulikki; Kok, Tuckweng; Manavis, Jim; Li, Peng; Mullbacher, Arno; Alsharifi, Mohammed

Description

We previously demonstrated that a single dose of nonadjuvanted intranasal γ-irradiated influenza A virus can provide robust protection in mice against both homologous and heterosubtypic challenges, including challenge with an H5N1 avian virus strain. We

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/39374
Source: Journal of Virology
DOI: 10.1128/JVI.02508-09

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