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Short Term Plasticity Provides Temporal Filtering at Chemical Synapses

Graham, Bruce P; Stricker, Christian


Chemical synapses exhibit a wide range of mechanisms that modulate the postsynaptic response due to presynaptic action potentials (APs) as a function of the arrival pattern of the presynaptic APs. Here we demonstrate that combinations of depression, facilitation and frequency-dependent recovery will give synapses that are either sensitive to the steady-state input signal, or to the onsets and offsets of signal transients. In addition, a synapse may be tuned to preferentially respond to low...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Book chapter
DOI: 10.1007/978-3-540-87559-8_28


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