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When birth comes early: effects on nephrogenesis

Black, Mary Jane; Sutherland, Megan R.; Gubhaju, Lina; Kent, Alison; Moore, Lynette; Dahlstrom, Jane


Preterm birth (birth prior to 37 completed weeks of gestation) may occur at a time when the infant kidney is very immature and nephrogenesis is often ongoing. In autopsied preterm human kidneys and in a baboon model of preterm birth it has been shown that nephrogenesis continues after preterm birth, with a significant increase in the number of glomerular generations and number of nephrons formed within the kidney after birth. Of concern, however, morphologically abnormal glomeruli (with a...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Nephrology
DOI: 10.1111/nep.12028


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