Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection
Date
2000
Authors
Riera, Ludovico
Gariglio, Marisa
Valente, Guido
Mullbacher, Arno
Museteanu, Crisan
Landolfo, Santo
Simon, Markus M
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Volume Title
Publisher
Wiley-VCH Verlag GMBH
Abstract
The course of mouse cytomegalovirus (MCMV) infection was compared between wild-type and mutant C57BL/6 (B6) mice deficient in either RAG-2, perforin, granzyme A, granzyme B or combinations thereof at two time points post infection (p.i.). At day 15 p.i.,
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Keywords
Keywords: CD8 antigen; granzyme A; granzyme B; perforin; animal experiment; animal model; animal tissue; article; controlled study; Cytomegalovirus; cytomegalovirus infection; disease course; inflammation; lung; mouse; natural killer cell; nonhuman; pathology; prio Granzyme; Murine cytomegalovirus replication; Perforin; RAG-2
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Source
European Journal of Immunology
Type
Journal article
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Restricted until
2037-12-31
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