A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration
A mouse neurological mutant, lister, was identified through a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Homozygous lister mice exhibit profound early-onset and progressive neurological and motor dysfunction. lister encodes a RING finger
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|Source:||PNAS - Proceedings of the National Academy of Sciences of the United States of America|
|01_Chu_A_mouse_forward_genetics_2009.pdf||1.12 MB||Adobe PDF||Request a copy|
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