Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat

Delghingaro-Augusto, Viviane; Décary, Simon; Peyot, Marie-Line; Latour, M.G; Lamontagne, Julien; Paradis-Isler, Nicolas; Lacharité-Lemieux, Marianne; Akakpo, Huguette; Birot, Olivier; Nolan, Christopher; Prentki, Marc; Bergeron, Raynald

Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat

Date

2012

Authors

Delghingaro-Augusto, Viviane

Décary, Simon

Peyot, Marie-Line

Latour, M.G

Lamontagne, Julien

Paradis-Isler, Nicolas

Lacharité-Lemieux, Marianne

Akakpo, Huguette

Birot, Olivier

Nolan, Christopher

Publisher

American Physiological Society

Abstract

Physical activity improves glycemic control in type 2 diabetes (T2D), but its contribution to preserving β-cell function is uncertain. We evaluated the role of physical activity on β-cell secretory function and glycerolipid/fatty acid (GL/FA) cycling in