Skip navigation
Skip navigation

Enantioselective total synthesis of (-)-Dactylolide

Louis, Ignace; Hungerford, Natasha; Humphries, Edward; McLeod, Malcolm


The enantioselective total synthesis of (-)-dactylolide is reported. The absolute stereochemistry of the tetrahydropyran was established by catalytic asymmetric Jacobsen hetero-Diels-Alder reaction. The remote C19 stereocenter was introduced by a sequence of chelation-controlled Grignard addition and Ireland-Claisen rearrangement.

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Organic Letters
DOI: 10.1021/ol053092b


File Description SizeFormat Image
01_Louis_Enantioselective_total_2006.pdf290.25 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator