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DMRT1 in a ratite bird: Evidence for a role in sex determination and discovery of a putative regulatory element

Shetty, S; Kirby, Patrick J; Zarkower, D; Graves, Jennifer

Description

Unlike mammals, birds have a ZZ male/ZW female sex-determining system. In most birds, the Z is large and gene rich, whereas the W is small and heterochromatic, but the ancient group of ratite birds are characterized by sex chromosomes that are virtually homomorphic. Any gene differentially present on the ratite Z and W is therefore a strong candidate for a sex-determining role. We have cloned part of the candidate bird sex-determining gene DMRT1 from the emu, a ratite bird, and have shown that...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/281492
Source: Cytogenetic and Genome Research
DOI: 10.1159/000071600

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