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CD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates

Norbury, Christopher; Basta, Sameh; Donohue, Keri B; Tscharke, David; Princiotta, Michael; Berglund, Peter; Gibbs, James; Bennink, Jack R; Yewdell, Jonathan W


"Cross-priming" describes the activation of naïve CD8 + T cells by professional antigen-presenting cells that have acquired viral or tumor antigens from "donor" cells. Antigen transfer is believed to be mediated by donor cell-derived molecular chaperones

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Science
DOI: 10.1126/science.1096378


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