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Mucosal HIV-1 Pox Virus Prime-Boost Immunization Induces High-Avidity CD8 + T Cells with Regime-Dependent Cytokine/Granzyme B Profiles

Ranasinghe, Charani; Turner, Stephen; McArthur, Craig; Sutherland, Duncan; Kim, Jee-Hye; Doherty, Peter; Ramshaw, Ian

Description

The quality of virus-specific CD8+ CTL immune responses generated by mucosal and systemic poxvinis prime-boost vaccines were evaluated in terms of T cell avidity and single-cell analysis of effector gene expression. Intranasal (I.N.) immunization regimes

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/26293
Source: Journal of Immunology

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