Dynamic and Responsive Growth Factor Delivery from Electrospun and Hydrogel Tissue Engineering Materials
Date
2017-11-30
Authors
Bruggeman, Kiara
Williams, Richard James
Nisbet, David
Journal Title
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Volume Title
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA.
Abstract
Tissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond mechanical and structural support, the next generation of these materials must also consider the more dynamic presentation and delivery of drugs or growth factors to guide new and regenerating tissue development. These two aspects are explored expansively separately, but they must interact synergistically to achieve optimal regeneration. This review explores common tissue engineering materials types, electrospun polymers and hydrogels, and strategies used for incorporating drug delivery systems into these scaffolds.
Description
Keywords
drug delivery, electrospinning, hydrogel, regenerative medicine, tissue engineering
Citation
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Source
Advanced Healthcare Materials
Type
Journal article
Book Title
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Restricted until
2099-12-31