Validation of verbal autopsy: determination of cause of deaths in Malaysia 2013
Date
2017
Authors
Ganapathy, Shubash Shander
Yi Yi, Khoo
Omar, Mohd Azahadi
Anuar, Mohamad Fuad Mohamad
Jeevananthan, Chandrika
Rao, Chalapati
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central Ltd.
Abstract
Background
Mortality statistics by age, sex and cause are the foundation of basic health data required for health status assessment, epidemiological research and formation of health policy. Close to half the deaths in Malaysia occur outside a health facility, are not attended by medical personnel, and are given a lay opinion as to the cause of death, leading to poor quality of data from vital registration. Verbal autopsy (VA) is a very useful tool in diagnosing broad causes of deaths for events that occur outside health facilities. This article reports the development of the VA methods and our principal finding from a validation study.
Methods
A cross sectional study on nationally representative sample deaths that occurred in Malaysia during 2013 was used. A VA questionnaire suitable for local use was developed. Trained field interviewers visited the family members of the deceased at their homes and conducted face to face interviews with the next of kin. Completed questionnaires were reviewed by trained physicians who assigned multiple and underlying causes. Reference diagnoses for validation were obtained from review of medical records (MR) available for a sample of the overall study deaths.
Results
Corresponding MR diagnosis with matched sample of the VA diagnosis were available in 2172 cases for the validation study. Sensitivity scores were good (>75%) for transport accidents and certain cancers. Moderate sensitivity (50% - 75%) was obtained for ischaemic heart disease (64%) and cerebrovascular disease (72%). The validation sample for deaths due to major causes such as ischaemic heart disease, pneumonia, breast cancer and transport accidents show low cause-specific mortality fraction (CSMF) changes. The scores obtained for the top 10 leading site-specific cancers ranged from average to good.
Conclusion
We can conclude that VA is suitable for implementation for deaths outside the health facilities in Malaysia. This would reduce ill-defined mortality causes in vital registration data, and yield more accurate national mortality statistics.
Description
Keywords
Verbal autopsy, Validation, Mortality, Cause of death
Citation
Collections
Source
BMC Public Health
Type
Journal article
Book Title
Entity type
Access Statement
Open Access
License Rights
Creative Commons License (Attribution 4.0 International)