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Modelling osteoblast adhesion on surface-engineered biomaterials: optimisation of nanophase grain size

Chen, Song; Lee, Cheuk; Li, Rachel; Smith, Paul; Qin, Qinghua


A double-layered model is proposed for numerically simulating osteoblast adhesion on surface-engineered biomaterials. The proposed model consists of molecular and cellular motions based on theoretical and experimental evidence and creates predictive simulations from sparse experimental data. The comparison of numerical solutions and experimental data reveals that the proposed model can explain the nonlinear behaviour of osteoblast adhesion on material surfaces in respect to nanophase grain size...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Computer Methods in Biomechanics and Biomedical Engineering
DOI: 10.1080/10255842.2017.1314468


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