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Algorithms for estimating rates of nucleotide change

Tang, Yurong

Description

The rapidly reducing cost of high throughput sequencing allows for the acquisition of genome-wide data for estimating nucleotide rates not only including mutation rates within species, but including substitution rates between species from multiple sequence alignments. To address the problem of estimating mutation rates within species, Vogl (2014) has developed a general algorithm for the case of bi-allelic neutral evolution. A necessary first step in generalizing the Vogl estimator to the...[Show more]

CollectionsOpen Access Theses
Date published: 2021
Type: Thesis (MPhil)
URI: http://hdl.handle.net/1885/236694
DOI: 10.25911/PKN3-JW82

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