N-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension
Date
2008
Authors
Krug, Susanne
Zhang, Yi
Mori, Trevor A
Croft, Kevin D
Vickers, Janine
Langton, Leanne
Whitworth, Judith
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Volume Title
Publisher
Blackwell Science Asia
Abstract
1. We have shown previously that N-acetylcysteine (NAC) prevents the increase in blood pressure induced by adrenocorticotropin treatment. The present study investigated the effect of NAC on dexamethasone (Dex)-induced hypertension. 2. Male Sprague-Dawley
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Keywords
Keywords: acetylcysteine; dexamethasone; isoprostane derivative; nitric oxide; sodium chloride; animal experiment; animal model; article; blood pressure measurement; controlled study; drug mechanism; fluid intake; food intake; hypertension; male; metabolism; nonhum Dexamethasone; Hypertension; N-acetylcysteine; Oxidative stress
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Source
Clinical and Experimental Pharmacology and Physiology
Type
Journal article
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2037-12-31
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