Skip navigation
Skip navigation

Fluid resuscitation in sepsis: the great 30 mL per kg hoax

Marik, Paul E.; Byrne, Liam; Van Haren, Frank


Large volume fluid resuscitation is currently viewed as the cornerstone of the treatment of septic shock. The surviving sepsis campaign (SSC) guidelines provide a strong recommendation to rapidly administer a minimum of 30 mL/kg crystalloid solution intravenously in all patients with septic shock and those with elevated blood lactate levels. However, there is no credible evidence to support this recommendation. In fact, recent findings from experimental, observational and randomized clinical...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
Source: Journal of Thoracic Disease
DOI: 10.21037/jtd.2019.12.84
Access Rights: Open Access


File Description SizeFormat Image
01_Marik_Fluid_resuscitation_in_sepsis%3A_2020.pdf286.64 kBAdobe PDFThumbnail

This item is licensed under a Creative Commons License Creative Commons

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator