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Fluid resuscitation in sepsis: the great 30 mL per kg hoax

Marik, Paul E.; Byrne, Liam; Van Haren, Frank

Description

Large volume fluid resuscitation is currently viewed as the cornerstone of the treatment of septic shock. The surviving sepsis campaign (SSC) guidelines provide a strong recommendation to rapidly administer a minimum of 30 mL/kg crystalloid solution intravenously in all patients with septic shock and those with elevated blood lactate levels. However, there is no credible evidence to support this recommendation. In fact, recent findings from experimental, observational and randomized clinical...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
URI: http://hdl.handle.net/1885/219244
Source: Journal of Thoracic Disease
DOI: 10.21037/jtd.2019.12.84
Access Rights: Open Access

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