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The Exploitation of Enzymatically-Derived cis-1,2-Dihydrocatechols and Related Compounds in the Synthesis of Biologically Active Natural Products

Taher, Ehab; Banwell, Martin; Buckler, Joshua; Yan, Qiao; Lan, Ping

Description

The title compounds of the general form 1 can be produced at large scale and in essentially enantiomerically pure form (when X≠H) through the whole cell biotransformation of the corresponding aromatic. The “dense” and varied functionality associated with these metabolites mean that they have become increasingly useful chirons for the total synthesis of a range of natural product types. This personal account details the outcomes of a nearly three‐decade long campaign within our group to exploit...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
URI: http://hdl.handle.net/1885/219215
Source: The Chemical Record
DOI: 10.1002/tcr.201700064

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