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Bisphosphonate guidelines for treatment and prevention of myeloma bone disease

Lee, Oi Lin; Horvath, N.; Lee, Cindy; Joshua, D; Ho, J; Szer, Jeff; Quach, H; Spencer, Andrew; Mollee, P; Roberts, Andrew A; Talaulikar, Dipti; Johnston, Anna M.


Multiple myeloma (MM) is a haematological malignancy characterised by the clonal proliferation of plasma cells in the bone marrow. More than 80% of patients with MM display evidence of myeloma bone disease (MBD), characterised by the formation of osteolytic lesions throughout the axial and appendicular skeleton. MBD significantly increases the risk of skeletal-related events such as pathologic fracture, spinal cord compression and hypercalcaemia. MBD is the result of MM plasma cells-mediated...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Internal Medicine Journal
DOI: 10.1111/imj.13502


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