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The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern

Prasanna, Thiru; Karapetis, C.S.; Roder, David; Tie, Jeanne; Padbury, Rob; Price, Timothy; Wong, Rachel; Shapiro, Jeremy; Nott, Louise M; Lee, Margaret; Chua, Yu Jo; Craft, Paul; Piantadosi, Cynthia; Sorich, Michael; Gibbs, Peter; Yip, Desmond


Background: Pattern of spread in patients with metastatic colorectal cancer (mCRC) is variable and may reflect different biology in subsets of patients. This is a retrospective study to explore the outcome of patients with mCRC based on their site of metastasis at diagnosis and to explore the association between tumor characteristics [KRAS/RAS, BRAF, mismatch repair (MMR) status, site of primary] and the site of metastasis. Methods: Patients from two Australian databases were divided into six...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Acta Oncologica
DOI: 10.1080/0284186X.2018.1487581


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