Yehya, Ashwaq H. S.; Asif, Muhammad; Tan, Yi J.; Sasidharan, Sreenivasan; Abdul Majid, Amin Malik Shah Bin; Oon, Chern Ein
Deregulated angiogenesis plays a central role in the development and metastasis of solid cancers. Tumor vasculature expressing a variety of biomarkers offers some novel therapeutic options which can be selectively targeted with anti-angiogenic agents without significantly affecting the normal vasculature. However, anti-angiogenic agents currently available commercially (synthetic compounds and humanized monoclonal antibodies) have been designed to target specific molecular markers within the...[Show more]
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