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Broad spectrum targeting of tumor vasculature by medicinal plants: An updated review

Yehya, Ashwaq H. S.; Asif, Muhammad; Tan, Yi J.; Sasidharan, Sreenivasan; Abdul Majid, Amin Malik Shah Bin; Oon, Chern Ein

Description

Deregulated angiogenesis plays a central role in the development and metastasis of solid cancers. Tumor vasculature expressing a variety of biomarkers offers some novel therapeutic options which can be selectively targeted with anti-angiogenic agents without significantly affecting the normal vasculature. However, anti-angiogenic agents currently available commercially (synthetic compounds and humanized monoclonal antibodies) have been designed to target specific molecular markers within the...[Show more]

CollectionsANU Research Publications
Date published: 2017-03-08
Type: Journal article
URI: http://hdl.handle.net/1885/195316
Source: Journal of Herbal Medicine
DOI: 10.1016/j.hermed.2017.03.003

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