A Naturally Occurring Novel Allele of Escherichia coli Outer Membrane Protein A Reduces Sensitivity to Bacteriophage
Date
2006
Authors
Power, Michelle L.
Ferrari, Belinda
Littlefield-Wyer, Jane
Gordon, David
Slade, Martin
Veal, Duncan
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Publisher
American Society for Microbiology
Abstract
A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele.
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Keywords
Keywords: Bacteria; Biological membranes; Encoding (symbols); Proteins; Bacteriophage resistance; Bacteriophage sensitivity testing; Cell surface proteins; Escherichia coli; bacteriophage receptor; cell surface protein; outer membrane protein A; allele; bacteriopha
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Source
Applied and Environmental Microbiology
Type
Journal article
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Open Access
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Restricted until
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